Desperate to reach her grieving mother, Mira joins a group of college students driving home after their flight is stranded, but the road conditions are not the only mortal danger they face.

Courtney is about to embark on a cross-country road trip to college with her boyfriend, Jordan, when he dumps her. Despite the breakup, they decide to go on the trip together.

Sixteen-year-old Sophie has been frail and delicate since her premature birth, but discovers her true strength during a journey through Mexico, where the six-year-old orphan her family hopes to adopt was born, and to Guatemala, where her would-be boyfriend hopes to find his mother and plans to remain.

When Buzz, his parents, and his pet fly go on a road trip and get lost, Fly Guy comes to the rescue to help them find their way home.

Sometimes you have to create your own destiny . . . Christy Knight grew up in Destiny, Ohio, but lately she feels that her future lies elsewhere. Her parents are gone and the beautiful jewelry she creates doesn't pay the bills. Maybe it's time for Christy to grow up and find a guy who's smart, sexy, and solvent. Her rugged handyman neighbor fits the first two categories, but he's all wrong for her. If only he didn't have such captivating blue eyes. Wary...

Cameron Smith, a disaffected sixteen year-old who, after being diagnosed with Creutzfeldt- Jakob's (aka mad cow) disease, sets off on a road trip with a death-obsessed video gaming dwarf he meets in the hospital in an attempt to find a cure.

Camille, seventeen, gives up her spot at a prestigious theater camp to drive from Texas to New Mexico to get an abortion, accompanied by her friends Annabelle and Bea.

Embarking on a Sunshine State road trip to meet long-lost family members, Serge Storms discovers that he may be related to a notorious serial killer before encountering a park ranger with her own mysterious agenda.

After her marriage falls apart and a hurricane destroys her home, Anne McWilliams sets off on a road trip to ask long lost friends and strangers one question, "What's your best story?", in an effort to find what she's been missing.

Stink Moody, friends Webster and Sophie, and Mrs. Birdwistle visit tourist attractions in Virginia as they try to give away 101 guinea pigs rescued from a laboratory, although Stink is very reluctant to give away his favorite, Astro.