House is serving a prison sentence for driving his car into Cuddy's living room, and when his sentence ends early, he finds the Diagnostic Medicine Department has gone through a transition in his absence and he must deal with a new chain of command and personnel changes to his team.

Return with Dr. Hank Lawson to the Hamptons, where the tides are high, bank account balances are higher, and the patients are just high maintenance. Because of his strong convictions and straight-shooting style, the 'concierge doctor's' practice is growing, and with the return of his estranged father, so is his family. See puzzling cases involving a faithful cop with an STD, a winemaker with a troubled palate, and a reality show where all the contestants...