Nanotechnology made humanity immortal, and the resulting population explosion pushed the Solar System's resources to the breaking point. As a result, new births are banned and even the planets' disparate governments cooperate to annihilate any children already born. With the tournament looming, Alita and her comrades find themselves caught between a spacefaring refuge for young innocents and a bloodthirsty mob intent on killing the children for sport!...

In the depths of Melchizedek, Alita inches closer to recovering her dear friend's brain but not before she is greeted by Mbadi and a rather duplicitous Desty Nova doppleganger. Meanwhile, Sechs and the other members of the Space Angels make their way through ZOTT, where Sechs comes to face a universally renowned Space Karate master in a show of technique, toughness and...thumbs?

Alita must construct a team of elite players in order to challenge Emperor Jasugun, champion of motorball: Caligula Armbrust, Aydakatti the Destroyer, Zafal Takie the Crimson Wind, and the ultimate black sheep, Tiegel... While she prepares for her greatest challenge yet, Jasugun is trapped in his own battle against fate. It all comes down to Alita's Panzer Kunst vs. Jasugun's Maschine Kratz. And in the midst of battle at the extreme limit of possibility,...

Two-hundred years in the future, Alita has returned to Mars to meet Erica. However, what should be a blissful reunion is anything but. A battle between two skilled practitioners of the Martian martial arts unfolds on the very grounds where their story began. Can Z.O.T.T. champion Alita best the prowess of Frau X?

Erica is now under the tutelage of Baron Muster, who has taken it upon himself to school her in the ways of villainy. Erica displays an uncanny knack for being bad, making her the perfect pupil, but her young mind and fresh perspectives also prove to be a boon in Muster's search for a legendary Martian treasure. With Erica's help, Muster and his team make it to a secret labyrinth that houses the famed treasure, but before Muster can finally get his...

In a dump in the lawless settlement of Scrapyard, far beneath the mysterious space city of Zalem, disgraced cyber-doctor Daisuke Ido makes a strange find: the detached head of a cyborg woman who has lost all her memories. He names her Alita and equips her with a powerful new body, the Berserker. While Alita remembers no details of her former life, a moment of desperation reawakens in her nerves the legendary school of martial arts known as Panzer...

Back with Ido again, life appears peaceful for Alita--until she learns that her former bounty-hunting companion Zapan is now a wanted man seeking unfair vengeance against her! Ido, meanwhile, follows the trail of transactions surrounding Alita's old Berserker body to the exiled Zalemite scientist Desty Nova. When Nova gives Zapan the body, it turns him into a demon sowing chaos everywhere. The "Zapan" arc is chock-full of rage, love, and pathos!!

Following her parting with Figure Four, Alita starts a new life as a TUNED agent with new powers. As she travels the desert, she's reunited with Koyomi, meets the eccentric blind psychometrist, Kaos--and comes into contact at last with Den, terrifying leader of Barjack. What is Alita's past, that Kaos claims to see? What is the purpose of the Barjack Rebellion, which spreads like wildfire?! As the cast expands, the "Barjack" arc reaches its most explosive...